This is the best part about growing. Choosing from the various mediums, lighting, nutrients, strains....
I'm currently running a kindsoil setup. It's a concentrated super soil placed at the bottom of a fabric pot, the rest is filled with any porous amended medium, in my case coco loco. I found out about it here on GWE and it sounded like a great fit for what I wanted to run.
Another one I want to try is Coco amended with earthworm castings. Later kelp, guano, fishmeal, and some other funky stuff gets added to the mix. All in an effort to maximize terpene and flavonoid production. Similar to a high brix concept.
I think organic growing is the cleanest, tastiest way to produce your meds. To each their own!
Good luck and welcome!