Hey Sledrock, not a pro by any means but i think that depends on your grow medium. This is my first time indoor, used terrible soil mix, probably 50% actual soil mixed with a garden store growing mix. I could never water till 20% run off..i would have to wait a week+ till next water. And soil that wet for that long brings a lot of other problems. I read an article here at GWE and it mentioned watering by weight. Thats what i did..and the girls are doing quite nicely. The only time i ever water till run off is to check my pH out. Hope some different medium growers will chime in here...im all ears cause next grow WONT be with actual soil