Howdy Farmbuck, If You are growing for the CBD content of the plants, I would keep them (just isolate them from the female plants). From what I have read, the male plants produce about the same amount of CBD's as the female plants do. I could be wrong (not the first time, or the last!). I have used some male plants (my first grow was male plants, I had never seen the plants naturally before and did not know how to tell them apart. They did provide some relief for my arthritis, but with out the 'high' effect.