OK, I think I know what the problem is with Blanca (and Betty to some extent):
calcium deficiency.
The first photo is Blanca. Note the
misshapen leaves, and the few
brown spots (upper leaf).
This is from an article about growing in Coco Coir. Note the
misshapen leaf in the first picture, and the
brown spots

The cause:
improper preparation of Coco Coir.
When I prepared the coco from a dry brick, I had followed the article
https://www.growweedeasy.com/coco-coir The article said:
"Optimally,
you can add a Cal-Mag supplement and pH this water to 6.0 before soaking. This can help make sure your coco coir has extra Calcium and also help it get into the right pH range right from the beginning.
Honestly though I often use water right out the tap. You’ll be adding Cal-Mag and setting the pH later, but the “best†way is to start supplementing your coco coir now, and it definitely may save you time and trouble later.
​
So, based on this, I
added a small amount of CalMag to the water when I rehydrated the coco -
about 1 ml/gallon.
However, today I read an article
https://www.cocoforcannabis.com/how-to-prepare-and-buffer-coco-coir/ that says to
buffer the Coco in a
much higher dose of CalMag, about 10x higher than I used - AND to do it for
two 8-hr soaks.
"There are cation exchange sites in coco that will interfere with nutrition until they are buffered. The cation exchange sites in coco naturally come loaded with sodium (Na) and potassium (K) cations. However, the Na and the K are only weakly held to the exchange sites. In the presence of calcium (Ca) or magnesium (Mg), the sites will release their Na or K cations and lock onto the Ca or Mg. These processes are known as “cation exchangesâ€.
"Buffering coco is accomplished by soaking it in Ca and Mg. This allows the cation exchanges to take place prior to adding plants. Simply soak your coco in a solution of Cal/Mag water and the exchange sites will release their K and Na cations and lock onto the Ca and Mg. When the cation exchange sites bond with Ca and Mg rather than Na and K, it is “bufferedâ€. The bonds that hold the Ca and Mg to the sites are very strong and cation exchange will largely stop. This means that all of the nutrients that you add to the water will be available to the plant at the ratios that you provide them."
​
I think the problems I'm seeing could be explained by
not doing a thorough enough Cal Mag treatment when preparing the Coco. They recommend a foliar spray with CalMag as a treatment.
​​​