Howdy Scooter, I had an issue with scales on a grow several years back. The only thing that killed them off and kept them from returning was by adding 10 ml of Azamax to the reservoir for several changes (I grow in hydro). Neem oil is organic, it is extracted from a plant. If You are growing in a 'live' soil, then I would apply it by a foilar spray because by drenching the soil, it might harm all of the beneficial nematodes and bacteria in the soil. In the hydroponic system it is taken up by the plant, become systemic and gets the critters that are feeding on the plant, a spray might not have any effect on the scale bugs because of their outer shell (or cover).