Depends on what u want to do tho them. Outdoor or indoor? When they are in veg u can do just about anything to them and they will recover. In general, once u have a plan start it, u want to remove some of the lower growth. Gets little light down there anyway. I grew a bunch of bag seeds just to see what I could and could not do to them. Some of them I downright abused. They all came back, even the ones that I striped bare and tried to dry it out. Just experiment.