Tom, my first thought was that the burned leaves looked like really bad nute burn that wasn't corrected.
Poor ventilation is not good for cannabis plants: air circulation is crucial. I think you're gambling if you have to leave them for long periods of time. Not the best conditions for tending to, taking care of, and keeping your eyes on what's going on with your girls.
I'd also suggest that you do some serious reading about what the plants need and how to supply that. You have to tune in the temp, humidity, air circulation, etc. according to the environment you live in. But even though this site is called GWE, it only gets easy if you know what you're doing.
For example, you have to be able to recognize the very first signs of nute burn on leaves, and adjust accordingly. Your plants got bad burn because that didn't happen. Most of us have been through these tough lessons, forked out $$$ to fine tune the growing environment (I dread to think of how much I've spent to get my girls in the right conditions for where I live), and learned to do it better. While cannabis plants can thrive on their own growing in their natural environments, when we bring them inside, there are a lot of different factors at play that we just plain old have to master. I'm still in this process; been growing for 21.5 months; 2 yrs. in July.
I have two grow boxes: a big one (BCNL RoomMate, excellent box) and a small one (a super closet that I would not recommend to anyone) that I only grow short plants (short Indicas) in. They have around 30" up to the light, so for the small grow box, I switch them to flower quick. I also included a pic of a sativa grow in the Roomie definitely outgrew the box.