It looks like a problem at the roots to me. Water isn't moving through the plant properly for some reason. It looks like it's in a very big pot for its size so I wonder if it might be overwatering? Are you waiting for the top inch to get dry before you water? How easily does the water drain out the bottom when you water and how long before you need to water again?
Did you do anything unusual right before it happened? Did you foliar feed or spray the plant with anything? Or water it with something new?
I noticed the humidity is really high (you want it closer to 50%). High humidity prevents the plant from uptaking water and nutrients properly, which might be making the problem worse though I don't think that could cause this. The way cannabis drinks is it evaporates water from the leaves, which sucks up water from the roots like a straw. If it's humid the plant isn't evaporating much water from the leaves and the plant stops being able to drink as much water. This makes it much more likely to suffer from problems with roots, overwatering and nutrient uptake because the plant takes forever to drink up the water in the pot. I think getting more oxygen to the roots by letting them dry out a little, alongside lowering your humidity, could help this plant recover. Though its a good idea to explore if you can figure out exactly what triggered the problem in the first place.