Howdy K Simpson32, Are You planning to use RO or distilled water for the grow? If so, one would need to supplement the minerals right from the start. I use the city tap water and because a good portion of the water supply is from well water, the calcium and magnesium is already there. I have not needed to supplement the water with any calcium or magnesium. You should be able to get a water report from your local water supplier that will list all minerals and other chemicals present in the water supply. If you are on a local well, you may not need to supplement it at all (depending on the soil and rock formations in your location). If you do have your own well, it can be tested by local agencies for content.