I can't see that anything bad could happen as a result of your crosses if you used good stock to start with. I hope you grow The Greatest Strain Of All Time. And, of course, I hope you'll be kind enough to send me a couple of seeds when that day comes. I've always been fascinated by plant genetics, although I've never bred my own plants. My wife wouldn't let me grow until 4 years ago, even though we are in CA. Long story. I managed a retail nursery for a couple of years long ago and later ran my own wholesale cactus business My pride were my fruit trees and my 250+ antique and bicolor rose garden. Now I live on top of a mountain of solid rock, can't grow anything that's not in some kind of container. Anyway, I'm very interested in your grow Thumbless Bastard, and I encourage you to get your spare bedroom set up for your breeding project soon. We aren't getting any younger y'know.