When I grow from seed and have normal alternating nodes, topping will usually result in the remaining tertiary nodes becoming dominant because of the auxins or growth hormones released in response to being topped. I then weave those nodes and repeat as necessary.
When I grow from clones, those are already sexually mature and have alternating nodes.
Topping those usually results in the lower nodes on those stems becoming dominant.
I like to allow them to get a bit leggy and then weave them into the trellis and THEN top.
That makes all of the lower nodes explode.