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as needed or when you feel like it . main things to avoid is taking too many leafs off at onetime or over stressing the plants. any big amounts of stress in flower could affect yield. even with a photoperiod plant. once flipped to 12/12 you have a limited time until the plant will stop producing
some people prefer taking all fan leafs off in week 1-2 of flower i prefer taking off whats needed throughout the entire grow
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