If you do defoliate, I wouldn't take much. She looks healthy so dont take it the wrong way, she isn't overwhelmingly bushy. The big water leaves you have currently may be doing the plant more good staying where they are for a while, meaning you can see the main stalk clearly already. Get her too thin and she may not produce like you hope both in potency as well as quantity, I thinned one so bad I probably lost over a unit in dried weight a while back.